You might have heard about a nasty vulnerability in Internet Explorer that allows a malicous website to remotely take-over one's machine. Microsoft just announced a fix for this issue that will be released tomorrow. It should be available via automatic updates, but just in case I'll follow up tomorrow with links.
The announcement:
http://www.microsoft.com/technet/security/bulletin/ms08-dec.mspx
More info about the vulnerability:
http://www.microsoft.com/technet/security/advisory/961051.mspx
If you previously applied any of the complex workarounds for this problem, you will need to reverse your changes before applying tomorrows update.